Calcitriol is an active metabolite from vitamin D3 which support Calcium absorption in intestinal and control bone-minerals.

Primary acting of Calcitriol is to manage the calcium-balance by stimulating the activity of osteoblast which is a pharmacological basis for osteoporosis therapy.

Composition

Each soft capsule contains :

Calcitriol 0,25 mcg

Calcitriol 0,5 mcg

Indication
o Established postmenopausal osteoporosis
o Renal osteodystrophy in patients with chronic renal impairment, particularly those undergoing hemodyalisis
o Postsurgical and idiopathic hypoparathyroidism
o Pseudohypoparathyroidism
o Vitamin D-dependent and hypophosphatemic vitamin D-resistant rickets

Contra Indication
Hypercalcemia; vitamin D toxicity

Warning
Pregnancy & lactation

Adverse Reaction
Weakness; dizziness; drowsiness; dry mouth; nausea; vomiting; constipation; muscular pain; bone pain; metallic taste; polyuria; polydipsia; anorexia; weight loss; nocturia; conjunctivitis; pancreatitis; photophobia; rhinorrhoea; hyperthermia; decreased libido; elevation in BUN levels; albuminuria; hypercholesterolemia; increased SGOT & SGPT; ectopic calcification; hypertension; cardiac arrhythmia

Dosage
Postmenopausal osteoporosis : 0,25 mcg twice daily
Renal osteodystrophy in patients on dialysis : initially 0,25 mcg daily or every other day. Usual dosage range 0,5 – 1 mcg daily
Hypoparathyroidsm & rickets : initially 0,25 mcg daily. Usual dosage range Adult 0,5 – 2 mcg daily, Children 1-5 years 0,25-0,75 mcg daily
Pre-dialysis patients :
Adult & children > 3 years initially 0,25 mcg daily. The dosage may be increased to 0,5 mcg daily. Chidren < 3 years 10-15 mcg/kg/day

Presentation
Box / 3 strip @ 10 soft capsules (Calcitriol 0,25 mcg)
Box / 3 strip @ 10 soft capsules (Calcitriol 0,5 mcg)