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Octalbin

Octalbin

Albumin is transporter-protein which is effective to treat severe icterus caused by haemolitic disease in neonatal. It has double-action therapy for acute-hepatic failure patient since its capability to raise plasma-oncotic pressure and bind excessive plasma bilirubin.

Octalbin is a human-serum albumin which may increase circulating blood volume and used for shock-therapy following by bleeding, surgery, traumatic, burnt, bacteremia, kidney failure, and cardiovascular collapse.

Composition

Each 100 ml Octalbin 20% contains Human Albumin 20 g

Each 100 ml Octalbin 25% contains Human Albumin 25 g

Indication
Restoration and maintenance of circulating blood volume, such as :
– Hypoalbuminemia in wound or burnt, cirrhosis, or nephrosis condition
– Cardiopulmonary bypass surgery
– Haemolitic disease in neonatal
Contra Indication
Patients who are hypersensitive to Albumin and other component consisted in human albumin; cardiac failure; and severe anemia
Warning
– Risk of hypervolaemia
– Monitor electrolyte status
– Not to be diluted with water for injection
– Stop therapy in CV overload
– Increased BP
– Raised venous pressure & pulmonary oedema
Adverse Reaction
Hypotension; flush; urticaria; fever; and nausea may rarely occur
Dosage
Albumin dosage generally for :
- adults : 2 g per kg body weight for 24 hours
- children : 0,5 – 1 g per kg body weight.
Direction
– Intravenously, Octalbin may or may not be diluted by normal saline or dextrose 5% before administration, or mixed with electrolyte solution in aseptic condition
– Infusion-administered velocity are individualized dosage, but not more than 1 – 2 ml/minute, and for plasma-exchange indication is not more than 30 ml/minute
– Before administration, it should be heated to room temperature, especially when it’s given in big volume
Presentation
Octalbin 20% solution 50 ml and 100 ml
Octalbin 25% solution 50 ml and 100 ml
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