apsul
FDA-APPROVED ANTIRETROVIRAL AGENTS
Generic Name
Proprietary
Name
Acronym Class
FDA
Approval
Zidovudine
Retrovir
AZT, ZDV
NRTI
1987
Didanosine
Videx
ddl NRTI
1991
Zalcitabine
Hivid
ddC NRTI
1992
Stavudine
Zerit
D4T NRTI
1994
Lamivudine
Epivir
3TC NRTI
1995
Abacavir
Ziagen
ABC NRTI
1998
Tenofovir
Viread
TDF NRTI
2001
Emtricitabine
Emtriva
FTC NRTI
2003
Nevirapine
Viramune
NVP NNRTI
1996
Delavaridine
Rescriptor
DLV NNRTI
1997
Efavirenz
Sustiva
EFV NNRTI
1998
Saquinavir
Fortovase
Invirase
SQV PI 1995
Ritonavir*
Norvir
RTV PI 1996
Indinavir
Crixivan
IDV PI 1996
Nelfinavir
Viracept
NFV PI 1997
Amprenavir
Agenerase
APV PI 1999
Lopinavir/f**
Kaletra
LPV/f PI 2000
Atazanavir
Reyataz
ATV PI 2003
Fosamprenavir
Lexiva
fAPV (908)
PI
2003
Enfuvirtide
Fuzeon
ENF (T20)
PI
2003
*May be used in a subtherapeutic dose, as a booster for other Pls, or in full dose.
**Used only in a booster form, in combination with ritonavir.
Keterangan :
o NRTI : nucleoside reverse transcriptase inhibitors
o NtRTI : nucleotide reverse transcriptase inhibitors
o NNRTI : nonnucleoside reverse transcriptase inhibitors
o PI : protease inhibitor
Sumber: http//www.medscape.com/viewarticle/470017_2
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