English Summary
THE EFFECT OF CENTELLA
ASIATICA
(L)
URBAN
PREPARATIONS THE FORM OF
OINTMENT, JELLY AND CREAM
ON BURNS
Suratman, Sri Adi Sumiwi,
Dolih Gozali
Dept. of Pharmacy. Faculty of Mathe-
matics and Physical Sciences, Padjadjar
an University, Bandung. Indonesia
A study on the healing effect
of extract of Centella asiatica(L.)
Urban in ointment, cream and
jelly basis on burns has been
carried out.
This study was done on male
Wistar rats, refered to Morton
Method. Examined dosage form
contained 3% and 5% of Centella
asiatica (L.) Urban extract
This study indicated that groups
that were given ointment, cream
and jelly that contain 3% of
extract recovered after 13th,12th
and 11th days respectively. And
the groups that were given oint-
ment cream and jelly that
contained 5% of extract reco-
vered after 12th, 11th and 11th
days respectively.
The statistical analysis con-
cluded that dosage form gave
no significant difference on
burned wound healing effect.
Cream and jelly had relatively
good stability in 3 months, while
ointment had bad stability.
Cermin Dunia Kedok. 1996; 108; 31-6
S, Sas, Dg
BACTERIAL RESISTANCE TOWARDS
AMINOGLYCOSIDES
Agus Sjahrurachman
Dept. of Microbiology. Faculty of Me-
dicine, University of Indonesia, Jakarta
Aminoglycosides are widely
used as antibiotics especially in
severe infections. Unfortunately
bacterial resistance towards
these drugs is increasing, the
pattern being that of a multi-
resistance.
To ensure efficient use of ami-
noglycosides, it is important to
comprehend the mechanisms of
resistance towards these drugs.
This paper discusses the deve-
lopment of resistance, stressing
the mechanisms of inactivation
of aminoglycosides by bacterial
enzymes.
Cermin Dunia Kedokt. 1996; 108: 49-53
Ssz
THE INFLUENCE OF SODIUM CHLO-
RIDE AND SODIUM BICARBONATE
PASTE ON GINGIVITIS
Prijantojo
Periodontology Lab., Faculty of Dentistry.
Universitas of Indonesia Jakarta
A double blind clinical trial to
assess the effect of sodium chlo-
ride and sodium bicarbonate
paste against gingival inflamma-
tion was carried out in 77 patients.
The study showed significant
reduction in gingival inflamma-
tion. The reduction of gingival
inflammation was 46% at day 7
and 77% at day 14. The contact
befween oral cavity hypertonic
solution and bacteria tend to with
draw water from living cell, so
suppressing the viability. Hyper-
tonic solution inhibit cell growth
and motility of oral spirochetes
which is the dominant microorga-
nism in gingival inflammation/
periodontal disease.
Cermin Dunia Kedokt. 1996; 108: 31-6
Pj
Cermin Dunia Kedokteran No. 108, 1996
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