English Summary
SEROLOGICAL EVALUATION OF
POLIO VACCINATION IN JAMBI
Gendrowahyuhono, Suharyono
Wuryadi
Communicable Diseases Research
Centre National Institute of Health Re-
search and Development Department
of Health, Jakarta, Indonesia
Study of evaluation of polio
vaccination in the children has
been carried out in Jambi, in 1982.
The objective of this study is to
determine, (1) immune response
to oral polio vaccine in the chil-
dren immunized with a standard
OPV I-II, (2) distribution of entero
viruses, (3) antibody status of the
children before immunization,
and (4) cold chain of polio
vaccines used in the field.
Two hundred children of 2 to
36 months old were randomly
sampled from the population in
Kodya Jambi. One hundred
children were immunized with
OPV I-II, and 100 children were
not immunized. Sera and rectal
swabs were taken from the
children, and examined by
neutralisation test and isolation
test respectively.
The result shows that, before
the children were immunized, 55%
of those children had no anti-
bodies at all to polio viruses. After
vaccination, seroconversion rates
to polio virus vaccine type 1, type
2, and type 3 were 86.6%, 83.9%,
and 92% respectively. Potency
test shows no reduction of the
vaccine potencies after it's
stored and used in the field.
Prevalence of enteroviruses
infections among the children,
before vaccination, were 18.7%
and decreased to 6% after vac-
cination.
It is concluded that, before
vaccination, the immune status
of the children under 3 years of
age were very low. Their immune
response to 2 doses of oral polio
vaccine were very good. The
distribution of enteroviruses in
the study area were high before
'vaccination, and decreased
sharply after vaccination. Cold
chain of the vaccines, during the
storage and after been used in
the field, were good.
It is suggested that children
under 3 years of age in the study
area should be vaccinated. Two
doses of oral polio vaccine is
sufficient for their basic immune
response.
Interference of Echo virus type
9 to the multiplication of polio
virus vaccine in the intestinal
tract and the development of
antibodies in the children were
discussed.
Cermin Dunia Kedokt, 1995; 100: 5-8
G
CHLORINE CONTAMINATION IN
KARET KUNINGAN SOUTH
JAKARTA
Sukar
Health Ecology Research Centre, Board
of Health Research and Development,
Department of Health, Jakarta, Indonesia
Chlorine compounds are irri-
tative and toxic through eye and
skin contact and are absorbed
by inhalation. The extensive use
of chlorine compounds in many
textile and batik-printing indus-
tries (as bleaching agent) makes
these compounds present in in-
dustrial emission and may con-
taminate the air. The study in Karet
Kuningan showed that at the
study location chlorine was de-
tectable (0,0293 ppm Cl
2
) while it
was undetectable at the control
location. Compared with the
standard in the United States
and Soviet Union, the chlorine
concentration at Karet Kuningan
Jakarta Selatan was not exceed-
ing the maximum allowable
concentration.
Cermin Dunia Kedokt. 1995; 100: 47-9
Sk
Cermin Dunia Kedokteran No. 101, 1995
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