Alamat Redaksi
Gedung KALBE
Jl. Letjen. Suprapto Kav. 4
Cempaka Putih, Jakarta 10510
Tlp: 021-4208171
Fax: 021-4287 3685
E-mail: cdk.redaksi@yahoo.co.id
http://twitter.com/CDKMagazine
Nomor Ijin
151/SK/DITJEN PPG/STT/1976 Tanggal 3 Juli 1976
Penerbit Kalbe Farma
Pencetak PT. Temprint
Susunan Redaksi
Ketua Pengarah
Dr. Boenjamin Setiawan, PhD
Pemimpin Umum
Dr. Erik Tapan
Ketua Penyunting
Dr. Budi Riyanto W.
Manajer Bisnis
Nofa, S.Si, Apt.
Dewan Redaksi
Prof. Dr. Sjahbanar Soebianto Zahir, MSc.
Dr. Michael Buyung Nugroho
Dr. Karta Sadana
Dr. Sujitno Fadli
Drs. Sie Djohan, Apt.
Ferry Sandra, Ph.D.
Budhi H. Simon, Ph.D.
Tata Usaha
Dodi Sumarna
CDK 173/vol.36 no.7/November - Desember 2009
477
ISSN: 0125-913 X
http://www.kalbe.co.id/cdk
ENGLISH SUMMARY
Stem Cell Unique cells
as gift from nature
Caroline T. Sardjono
Department of Microbiology, Faculty of Medicine,
Maranatha Christian University,
Bandung, Indonesia
Stem Cell and Cancer Institute, Jakarta, Indonesia
Nature gives all living organisms capabili-
ties to survive many challenges during their
life; including cells and organs regenera-
tion like regeneration of injured skin and
continued supply of blood cells. The rege-
neration process is executed by stem cells.
Thus, stem cells clearly play an important
part in the development, maturation, and
regeneration process throughout the body.
Recently, knowledge in stem cell biology
has lead medical science to develop poten-
tial therapy using stem cells for many
diseases including malignancy, hemato-
logical abnormalities, and degenerative
diseases. Moreover, stem cells can be stored
longer for future usage, ex-vivo expanded,
differentiated, and generated into specific
organs.
The fast development in stem cell therapy
is very exciting.
CDK 2009; 36(7) : 479-482
Epilepsy is one of the major neurological
diseases in childhood with complex problems.
Knowledge on epilepsy prognosis and its
prognostic factors are very important for
providing adequate information and mana-
gement planning.
This study includes 110 epilepsy patients -
42,7% male 57,3% female. Six-month
remission within 2 years medication was
achieved in 86 patients (78,2%).
The significant predictive factors for not
achieving 6-month remission are seizure
type, number of pre treatment seizure, and
the presence of neurological deficit.
Twelve-month remission was achieved by
48 patients (43,6%). The significant predic-
tive factors for not achieving 12-month
remission were high frequency pre-treat-
ment seizure, presence of neurological
deficit, and noncompliance.
Key words: epilepsy-childhood and young-
adult onset- remission- prognosis
CDK 2009; 36(7) : 493-496
Prune belly syndrome (PBS) is a congenital
anomaly syndrome characterized by triad
of abdominal musculature deficiency, ano-
malous development of the urinary tract,
and bilateral cryptorchidism.
The syndrome seems to be sporadic affect-
ing predominantly boys. Etiopathophysio-
logy of PBS remains unknown but may be
caused by primary mesodermal development
defect. PBS can be detected intrauterine
with fetal ultrasound and in newborn with
typical triad of clinical features consist of
wrinkled appearance of the abdominal skin
mimicking a prune fruit, bilateral cryptor-
chidism, and bladder distension. Radiologic
findings could detect present defects.
Management includes supportive therapy
and surgical intervention. Prognosis depends
on the degree of pulmonary and renal dys-
plasia, degree of urinary tract obstruction,
and the severity of urinary tract infection.
CDK 2009; 36(7) : 498-501
Profiles of Remission
among Childhood-onset
Epilepsy
Rizaldy Pinzon
1
, Harsono
2
, Imam Rusdi
2
1
Dept. of Neurology, Bethesda Hospital,
Yogyakarta
2
Dept. of Neurology, Faculty of Medicine,
Gadjah Mada University, Yogyakarta
Prune Belly Syndrome
Husein Albar
Dept. of Pediatrics, Wahidin Sudirohusodo
Hospital / Hasanuddin Univeristy, Makassar,
South Sulawesi, Indonesia
478
CDK 173/vol.36 no.7/November - Desember 2009
Redaksi Kehormatan
Prof. Drg. Siti Wuryan A Prayitno, SKM, MScD, PhD
Bagian Periodontologi, Fakultas Kedokteran Gigi Universitas Indonesia, Jakarta
Prof. Dr. Abdul Muthalib, SpPD KHOM
Divisi Hematologi Onkologi Medik
Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Indonesia/
RSUPN Dr. Cipto Mangunkusumo, Jakarta
Prof. Dr. Djoko Widodo, SpPD-KPTI
Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Indonsia/
RSUPN Dr. Cipto Mangunkusumo, Jakarta
Prof. DR. Dr. Charles Surjadi, MPH
Pusat Penelitian Kesehatan Unika Atma Jaya Jakarta
Prof. DR. Dr. H. Azis Rani, SpPD, KGEH
Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Indonesia/
RSUPN Dr. Cipto Mangunkusumo, Jakarta
Prof. DR. Dr. Sidartawan Soegondo, SpPD, KEMD, FACE
Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Indonesia/
RSUPN Dr. Cipto Mangunkusumo, Jakarta
DR. Dr. Abidin Widjanarko, SpPD-KHOM
Fakultas Kedokteran Universitas Indonesia/RS Kanker Dharmais, Jakarta
DR. Dr. med. Abraham Simatupang, MKes
Bagian Farmakologi, Fakultas Kedokteran Universitas Kristen Indonesia, Jakarta
Prof. Dr. Sarah S. Waraouw, SpA(K)
Dekan Fakultas Kedokteran Universitas Sam Ratulangi, Manado
Prof. DR. Dr. Rully M.A. Roesli, SpPD-KGH
Bagian Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Padjadjaran/
RSUP Dr. Hasan Sadikin, Bandung
Dr. Aucky Hinting, PhD, SpAnd
Bagian Biomedik Fakultas Kedokteran Universitas Airlangga Surabaya
DR. Dr. Yoga Yuniadi, SpJP
Departemen Kardiologi dan Kedokteran Vaskular FKUI/
Pusat Jantung Nasional Harapan Kita, Jakarta
Prof. DR. Dra. Arini Setiawati
Bagian Farmakologi Fakultas Kedokteran Universitas Indonesia, Jakarta
Prof. Dr. Faisal Yunus, PhD, SpP(K)
Departemen Pulmonologi & Ilmu Kedokteran Respirasi Fakultas Kedokteran
Universitas Indonesia/SMF Paru RS Persahabatan, Jakarta
Prof. DR. Dr. Rianto Setiabudy, SpFK
Bagian Farmakologi Fakultas Kedokteran Universitas Indonesia, Jakarta
Dr. R.M. Nugroho Abikusno, MSc., DrPH
Fakultas Kedokteran Universitas Trisakti, Jakarta
Prof. DR. Dr. Wimpie Pangkahila, SpAnd, FAACS
Fakultas KedokteranUniversitas Udayana Denpasar, Bali
Prof. DR. Dr. Ignatius Riwanto, SpB(K)
Bagian Bedah Fakultas Kedokteran Universitas Diponegoro/
RS Dr. Kariadi, Semarang
Dr. Tony Setiabudhi, SpKJ, PhD
Universitas Trisakti/ Pusat Kajian Nasional Masalah Lanjut Usia, Jakarta
Prof. DR. Samsuridjal Djauzi, SpPD, KAI
Sub Dept. Alergi-Imunologi, Dept. Ilmu Penyakit Dalam Fakultas Kedokteran
Universitas Indonesia/RSUPN Dr. Cipto Mangunkusumo, Jakarta
Dr. Prijo Sidipratomo, SpRad(K)
Departemen Radiologi FKUI/RSUPN Dr. Cipto Mangunkusumo, Jakarta
Prof. DR. Dr. Johan S. Masjhur, SpPD-KEMD, SpKN
Departemen Kedokteran Nuklir Fakultas Kedokteran Universitas Padjadjaran/
RSUP Dr. Hasan Sadikin, Bandung
Dr. Hendro Susilo, SpS(K)
Dept. Neurologi Fakultas Kedokteran Universitas Airlangga/RS Dr. Soetomo,
Surabaya
Prof. DR. Dr. Darwin Karyadi, SpGK
Institut Pertanian Bogor, Bogor, Jawa Barat
Dr. Ike Sri Redjeki, SpAn KIC, M.Kes
Bagian Anestesiologi & Reanimasi Fakultas Kedokteran Universitas Padjadjaran/
RSUP Dr. Hasan Sadikin, Bandung